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Engineered bacteria function in the mammalian gut as long term live diagnostics of inflammation

Bacteria can be engineered to function as diagnostics or therapeutics in the mammalian gut but commercial translation of these technologies has been hindered by the susceptibility of synthetic genetic circuits to mutation and unpredictable function during extended gut colonization. Here we report st...

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Bibliografiske detaljer
Udgivet i:Nat Biotechnol
Main Authors: Riglar, David T, Giessen, Tobias W, Baym, Michael, Kerns, S Jordan, Niederhuber, Matthew J, Bronson, Roderick T, Kotula, Jonathan W, Gerber, Georg K, Way, Jeffrey C, Silver, Pamela A
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5658125/
https://ncbi.nlm.nih.gov/pubmed/28553941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3879
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