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Stable Neutralization of a Virulence Factor in Bacteria Using Temperate Phage in the Mammalian Gut

Elimination or alteration of select members of the gut microbiota is key to therapeutic efficacy. However, the complexity of these microbial inhabitants makes it challenging to precisely target bacteria. Here, we deliver exogenous genes to specific bacteria by genomic integration of temperate phage...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Hsu, Bryan B., Way, Jeffrey C., Silver, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6989128/
https://ncbi.nlm.nih.gov/pubmed/31992629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00013-20
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