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Programmable bacteria detect and record an environmental signal in the mammalian gut

The mammalian gut is a dynamic community of symbiotic microbes that interact with the host to impact health, disease, and metabolism. We constructed engineered bacteria that survive in the mammalian gut and sense, remember, and report on their experiences. Based on previous genetic memory systems, w...

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Detalhes bibliográficos
Main Authors: Kotula, Jonathan W., Kerns, S. Jordan, Shaket, Lev A., Siraj, Layla, Collins, James J., Way, Jeffrey C., Silver, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977281/
https://ncbi.nlm.nih.gov/pubmed/24639514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1321321111
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