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Mammalian Cells Engineered to Produce Novel Steroids

Steroids can be difficult to modify via traditional organic synthesis methods, but many enzymes regio- and stereo-selectively process a wide variety of steroid substrates. We tested whether steroid-modifying enzymes could make novel steroids from non-native substrates. Numerous genes encoding steroi...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Spady, Emma S., Wyche, Thomas P., Rollins, Nathanael J., Clardy, Jon, Way, Jeffrey C., Silver, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156985/
https://ncbi.nlm.nih.gov/pubmed/29931794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800214
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