Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity

Reduced activity of nutrient-sensing signaling networks can extend organismal lifespan, yet the underlying biology remains unclear. We show that the anti-aging effects of rapamycin and reduced intestinal insulin/insulin growth factor (IGF) signaling (IIS) require the Drosophila FoxA transcription fa...

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Pubblicato in:Cell Rep
Autori principali: Bolukbasi, Ekin, Khericha, Mobina, Regan, Jennifer C., Ivanov, Dobril K., Adcott, Jennifer, Dyson, Miranda C., Nespital, Tobias, Thornton, Janet M., Alic, Nazif, Partridge, Linda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656751/
https://ncbi.nlm.nih.gov/pubmed/29045833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.09.042
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