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Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction
Women live on average longer than men but have greater levels of late-life morbidity. We have uncovered a substantial sex difference in the pathology of the aging gut in Drosophila. The intestinal epithelium of the aging female undergoes major deterioration, driven by intestinal stem cell (ISC) divi...
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Publicado no: | eLife |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
eLife Sciences Publications, Ltd
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4805549/ https://ncbi.nlm.nih.gov/pubmed/26878754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10956 |
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