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Real-time in vivo mitochondrial redox assessment confirms enhanced mitochondrial reactive oxygen species in diabetic nephropathy

While increased mitochondrial reactive oxygen species have been commonly implicated in a variety of disease states, their in vivo role in the pathogenesis of diabetic nephropathy remains controversial. Using a two-photon imaging approach with a genetically encoded redox biosensor, we monitored mitoc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Kidney Int
Hauptverfasser: Galvan, Daniel L., Badal, Shawn S., Long, Jianyin, Chang, Benny H., Schumacker, Paul T., Overbeek, Paul A., Danesh, Farhad R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5656393/
https://ncbi.nlm.nih.gov/pubmed/28754553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2017.05.015
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