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Ubiquitination of STING at lysine 224 controls IRF3 activation()
Cytosolic DNA species derived from invading microbes or leaked from the nuclear or mitochondrial compartments of the cell can trigger the induction of host defense genes by activating the endoplasmic reticulum (ER)-associated protein STING. Using a mass spectrometry based approach, we show that afte...
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| Publicado no: | Sci Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5656267/ https://ncbi.nlm.nih.gov/pubmed/28763789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aah7119 |
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