Activation of STING requires palmitoylation at the Golgi

Stimulator of interferon genes (STING) is essential for the type I interferon response against DNA pathogens. In response to the presence of DNA and/or cyclic dinucleotides, STING translocates from the endoplasmic reticulum to perinuclear compartments. However, the role of this subcellular transloca...

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Pubblicato in:Nat Commun
Autori principali: Mukai, Kojiro, Konno, Hiroyasu, Akiba, Tatsuya, Uemura, Takefumi, Waguri, Satoshi, Kobayashi, Toshihide, Barber, Glen N., Arai, Hiroyuki, Taguchi, Tomohiko
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919521/
https://ncbi.nlm.nih.gov/pubmed/27324217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11932
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