Homeostatic regulation of STING by retrograde membrane traffic to the ER

Coat protein complex I (COP-I) mediates the retrograde transport from the Golgi apparatus to the endoplasmic reticulum (ER). Mutation of the COPA gene, encoding one of the COP-I subunits (α-COP), causes an immune dysregulatory disease known as COPA syndrome. The molecular mechanism by which the impa...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mukai, Kojiro, Ogawa, Emari, Uematsu, Rei, Kuchitsu, Yoshihiko, Kiku, Fumika, Uemura, Takefumi, Waguri, Satoshi, Suzuki, Takehiro, Dohmae, Naoshi, Arai, Hiroyuki, Shum, Anthony K., Taguchi, Tomohiko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782846/
https://ncbi.nlm.nih.gov/pubmed/33397928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20234-9
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