STING palmitoylation as a therapeutic target

Gain-of-function mutations in the STING-encoding gene TMEM173 are central to the pathology of the autoinflammatory disorder STING-associated vasculopathy with onset in infancy (SAVI). Furthermore, excessive activity of the STING signaling pathway is associated with autoinflammatory diseases, includi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Mol Immunol
Prif Awduron: Hansen, Anne Louise, Mukai, Kojiro, Schopfer, Francisco J., Taguchi, Tomohiko, Holm, Christian K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2019
Pynciau:
Review Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460494/
https://ncbi.nlm.nih.gov/pubmed/30796349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-019-0205-5
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