Expansion of BCR/ABL1 (+) cells requires PAK2 but not PAK1

The p21‐activated kinases (PAKs) are key nodes in oncogenic signalling pathways controlling growth, survival, and motility of cancer cells. Their activity is increased in many human cancers and is associated with poor prognosis. To date, PAK deregulation has mainly been studied in solid tumours, whe...

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Dades bibliogràfiques
Publicat a:Br J Haematol
Autors principals: Edlinger, Leo, Berger‐Becvar, Angelika, Menzl, Ingeborg, Hoermann, Gregor, Greiner, Georg, Grundschober, Eva, Bago‐Horvath, Zsuzsanna, Al‐Zoughbi, Wael, Hoefler, Gerald, Brostjan, Christine, Gille, Lars, Moriggl, Richard, Spittler, Andreas, Sexl, Veronika, Hoelbl‐Kovacic, Andrea
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Haematological Malignancy
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655792/
https://ncbi.nlm.nih.gov/pubmed/28707321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14833
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