Expansion of BCR/ABL1 (+) cells requires PAK2 but not PAK1

The p21‐activated kinases (PAKs) are key nodes in oncogenic signalling pathways controlling growth, survival, and motility of cancer cells. Their activity is increased in many human cancers and is associated with poor prognosis. To date, PAK deregulation has mainly been studied in solid tumours, whe...

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Detaylı Bibliyografya
Yayımlandı:Br J Haematol
Asıl Yazarlar: Edlinger, Leo, Berger‐Becvar, Angelika, Menzl, Ingeborg, Hoermann, Gregor, Greiner, Georg, Grundschober, Eva, Bago‐Horvath, Zsuzsanna, Al‐Zoughbi, Wael, Hoefler, Gerald, Brostjan, Christine, Gille, Lars, Moriggl, Richard, Spittler, Andreas, Sexl, Veronika, Hoelbl‐Kovacic, Andrea
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2017
Konular:
Haematological Malignancy
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655792/
https://ncbi.nlm.nih.gov/pubmed/28707321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.14833
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