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PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis
The transcription factor STAT5 (signal transducer and activator of transcription 5) is frequently activated in hematological malignancies and represents an essential signaling node downstream of the BCR-ABL oncogene. STAT5 can be phosphorylated at three positions, on a tyrosine and on the two serine...
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| Auteurs principaux: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948164/ https://ncbi.nlm.nih.gov/pubmed/24263804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2013.351 |
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