STAT5 triggers BCR-ABL1 mutation by mediating ROS production in chronic myeloid leukaemia

We recently reported that chronic myeloid leukaemia (CML) patients harbour high levels of STAT5 when they progress to advanced phases of disease. Advanced disease is characterized by an increased incidence of BCR-ABL1 mutations. We now describe a highly significant correlation between STAT5 expressi...

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Autores principales: Warsch, Wolfgang, Grundschober, Eva, Berger, Angelika, Gille, Lars, Cerny-Reiterer, Sabine, Tigan, Anca-Sarmiza, Hoelbl-Kovacic, Andrea, Valent, Peter, Moriggl, Richard, Sexl, Veronika
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3681503/
https://ncbi.nlm.nih.gov/pubmed/23458731
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