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Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice

Polo-like kinase 1 (Plk1), a serine/threonine protein kinase normally expressed in mitosis, is frequently up-regulated in multiple types of human tumors regardless of the cell cycle stage. However, the causal relationship between Plk1 up-regulation and tumorigenesis is incompletely investigated. To...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Li, Zhiguo, Liu, Jinghui, Li, Jie, Kong, Yifan, Sandusky, George, Rao, Xi, Liu, Yunlong, Wan, Jun, Liu, Xiaoqi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655521/
https://ncbi.nlm.nih.gov/pubmed/28900036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.810960
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