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Polo-like kinase (Plk)1 depletion induces apoptosis in cancer cells
Elevated expression of mammalian polo-like kinase (Plk)1 occurs in many different types of cancers, and Plk1 has been proposed as a novel diagnostic marker for several tumors. We used the recently developed vector-based small interfering RNA technique to specifically deplete Plk1 in cancer cells. We...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The National Academy of Sciences
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC156279/ https://ncbi.nlm.nih.gov/pubmed/12732729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1031523100 |
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