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Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice
Polo-like kinase 1 (Plk1), a serine/threonine protein kinase normally expressed in mitosis, is frequently up-regulated in multiple types of human tumors regardless of the cell cycle stage. However, the causal relationship between Plk1 up-regulation and tumorigenesis is incompletely investigated. To...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655521/ https://ncbi.nlm.nih.gov/pubmed/28900036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.810960 |
| Oznake: |
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