Caricamento...

HDAC6 inhibitor WT161 downregulates growth factor receptors in breast cancer

We have shown that WT-161, a histone deacetylase 6 (HDAC6) inhibitor, shows remarkable anti-tumor activity in multiple myeloma (MM) in preclinical models. However, its activity in other type of cancers has not yet been shown. In this study, we further evaluated the biologic sequelae of WT161 in brea...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Hideshima, Teru, Mazitschek, Ralph, Qi, Jun, Mimura, Naoya, Tseng, Jen-Chieh, Kung, Andrew L., Bradner, James E., Anderson, Kenneth C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655183/
https://ncbi.nlm.nih.gov/pubmed/29113288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19019
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !