HDAC6 inhibitor WT161 performs anti-tumor effect on osteosarcoma and synergistically interacts with 5-FU

Background: WT161, as a selective HDAC6 inhibitor, has been shown to play anti-tumor effects on several kinds of cancers. The aim of the present study is to explore the roles of WT161 in osteosarcoma and its underlying mechanisms. Methods: The anti-proliferative effect of WT161 on osteosarcoma cells...

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Dades bibliogràfiques
Publicat a:Biosci Rep
Autors principals: Sun, Jun, Wu, Wei, Tang, Xiaofeng, Zhang, Feifei, Ju, Cheng, Liu, Renfeng, Liang, Yiping, Yu, Bo, Lv, Bin, Guo, Yuhong, Zeng, Duo, Tao, Xuchang, Wang, Min, Zhang, Zhiping, Zhang, Changhua, Lv, Xiao-Bin
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2021
Matèries:
Cancer
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8150159/
https://ncbi.nlm.nih.gov/pubmed/33860796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20203905
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