טוען...
Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
Over 80% of multiple-tested siRNAs and shRNAs targeting CD95 or CD95 ligand (CD95L) induce a form of cell death characterized by simultaneous activation of multiple cell death pathways preferentially killing transformed and cancer stem cells. We now show these si/shRNAs kill cancer cells through can...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5655136/ https://ncbi.nlm.nih.gov/pubmed/29063830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29702 |
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