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CD95/Fas ligand mRNA is toxic to cells
CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is enriched in sequences that, when converted to si/shRNAs, kill all cancer cells by targeting critical survival genes (Putzbach et al., 2017). We now report expression of...
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| Опубликовано в: : | eLife |
|---|---|
| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
eLife Sciences Publications, Ltd
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6191286/ https://ncbi.nlm.nih.gov/pubmed/30324908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38621 |
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