Llwytho...

DISE - A Seed Dependent RNAi Off-Target Effect that Kills Cancer Cells

Off-target effects (OTE) present a significant caveat of RNA interference (RNAi) caused by substantial complementarity between small interfering (si)RNAs and unintended mRNAs. We now discuss the existence of three types of seed dependent (s)OTEs: Type I involves unintended targeting through the guid...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Cancer
Prif Awduron: Putzbach, William, Gao, Quan Q., Patel, Monal, Haluck-Kangas, Ashley, Murmann, Andrea E., Peter, Marcus E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806146/
https://ncbi.nlm.nih.gov/pubmed/29413418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2017.11.007
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!