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Effects of Echinocandins in Combination with Nikkomycin Z against Invasive Candida albicans Bloodstream Isolates and the fks Mutants

We evaluated the in vitro and in vivo effects of nikkomycin Z combined with an echinocandin (anidulafungin or micafungin) against two Candida albicans isolates and their lab-derived echinocandin-resistant fks mutants with FKS1 S645Y and FKS1 S645P. Synergistic effects were observed in all tested str...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Cheung, Yuk-Yam, Hui, Mamie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655089/
https://ncbi.nlm.nih.gov/pubmed/28827418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00619-17
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