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In Vitro Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae

We evaluated the activity of the novel semisynthetic pleuromutilin lefamulin, inhibiting protein synthesis and growth, and the effect of efflux pump inactivation on clinical gonococcal isolates and reference strains (n = 251), including numerous multidrug-resistant and extensively drug-resistant iso...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Jacobsson, Susanne, Paukner, Susanne, Golparian, Daniel, Jensen, Jörgen S., Unemo, Magnus
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655042/
https://ncbi.nlm.nih.gov/pubmed/28893785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01497-17
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