In Vitro Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae

We evaluated the activity of the novel semisynthetic pleuromutilin lefamulin, inhibiting protein synthesis and growth, and the effect of efflux pump inactivation on clinical gonococcal isolates and reference strains (n = 251), including numerous multidrug-resistant and extensively drug-resistant iso...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Jacobsson, Susanne, Paukner, Susanne, Golparian, Daniel, Jensen, Jörgen S., Unemo, Magnus
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Susceptibility
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655042/
https://ncbi.nlm.nih.gov/pubmed/28893785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01497-17
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