In Vitro Activity of the Novel Pleuromutilin Lefamulin (BC-3781) and Effect of Efflux Pump Inactivation on Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae

We evaluated the activity of the novel semisynthetic pleuromutilin lefamulin, inhibiting protein synthesis and growth, and the effect of efflux pump inactivation on clinical gonococcal isolates and reference strains (n = 251), including numerous multidrug-resistant and extensively drug-resistant iso...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Jacobsson, Susanne, Paukner, Susanne, Golparian, Daniel, Jensen, Jörgen S., Unemo, Magnus
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Susceptibility
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5655042/
https://ncbi.nlm.nih.gov/pubmed/28893785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01497-17
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