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Genome variation across cancers scales with tissue stiffness – an invasion-mutation mechanism and implications for immune cell infiltration
Many different types of soft and solid tumors have now been sequenced, and meta-analyses suggest that genomic variation across tumors scales with the stiffness of the tumors’ tissues of origin. The opinion expressed here is based on a review of current genomics data, and it considers multiple ‘mecha...
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| Publicado no: | Curr Opin Syst Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5654613/ https://ncbi.nlm.nih.gov/pubmed/29082336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coisb.2017.04.005 |
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