載入...
Elastic-Fluid Model for DNA Damage and Mutation from Nuclear Fluid Segregation Due to Cell Migration
When cells migrate through constricting pores, they incur DNA damage and develop genomic variation. Experiments show that this damage is not due to DNA breakage from mechanical stress on chromatin in the deformed nucleus. Here we propose a model for a mechanism by which nuclear deformation can lead...
Na minha lista:
| 發表在: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Biophysical Society
2017
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474726/ https://ncbi.nlm.nih.gov/pubmed/28591600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.04.037 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|