Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

Urinary tract infections (UTI) caused by uropathogenic E. coli (UPEC) affect 150 million people annually(1,2). Despite effective antibiotic therapy, 30–50% of patients experience recurrent UTI (rUTI)(1). Additionally, the growing prevelance of UPEC resistant to last-line antibiotic treatments, and m...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Spaulding, Caitlin N., Klein, Roger D., Ruer, Ségolène, Kau, Andrew L., Schreiber, Henry L., Cusumano, Zachary T., Dodson, Karen W., Pinkner, Jerome S., Fremont, Daved H., Janetka, James W., Remaut, Han, Gordon, Jeffrey I., Hultgren, Scott J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654549/
https://ncbi.nlm.nih.gov/pubmed/28614296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22972
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