Preclinical effects of APOE ε4 on cerebrospinal fluid Aβ42 concentrations

BACKGROUND: From earlier studies it is known that the APOE ε2/ε3/ε4 polymorphism modulates the concentrations of cerebrospinal fluid (CSF) beta-amyloid(1–42) (Aβ42) in patients with cognitive decline due to Alzheimer’s disease (AD), as well as in cognitively healthy controls. Here, in a large cohort...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Lautner, Ronald, Insel, Philip S., Skillbäck, Tobias, Olsson, Bob, Landén, Mikael, Frisoni, Giovanni B., Herukka, Sanna-Kaisa, Hampel, Harald, Wallin, Anders, Minthon, Lennart, Hansson, Oskar, Blennow, Kaj, Mattsson, Niklas, Zetterberg, Henrik
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5654097/
https://ncbi.nlm.nih.gov/pubmed/29061195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0313-3
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires