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Increased amyloidogenic APP processing in APOE ɛ4-negative individuals with cerebral β-amyloidosis
Increased APP (amyloid precursor protein) processing causes β-amyloid (Aβ) accumulation in autosomal dominant Alzheimer's disease (AD), but it is unclear if it also affects sporadic Aβ accumulation. We tested healthy controls and patients with mild cognitive symptoms (N=331) in the BioFINDER st...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4786682/ https://ncbi.nlm.nih.gov/pubmed/26948379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10918 |
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