Formal Synthesis of (+)-Laurencin via a Gold(I)-Catalyzed Intramolecular Dehydrative Alkoxylation

8-Membered cyclic ethers are found in a wide range of natural products; however, they are challenging synthetic targets due to enthalpic and entropic barriers. The gold(I)-catalyzed intramolecular dehydrative alkoxylation of ω-hydroxy allylic alcohols was explored to stereoselectively construct α,α′...

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Bibliographic Details
Published in:Chemistry
Main Authors: Lanier, Megan L., Park, Hyeri, Mukherjee, Paramita, Timmerman, Jacob C., Ribeiro, Anthony A., Widenhoefer, Ross A., Hong, Jiyong
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653968/
https://ncbi.nlm.nih.gov/pubmed/28393406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700499
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