METFORMIN AMELIORATES GENDER- AND AGE-DEPENDENT HEMODYNAMIC INSTABILITY AND MYOCARDIAL INJURY IN MURINE HEMORRHAGIC SHOCK

Severity of multiple organ failure is significantly impacted by age and gender in patients with hemorrhagic shock. However, the molecular mechanisms underlying the enhanced organ injury are not fully understood. AMP-activated protein kinase (AMPK) is a pivotal orchestrator of metabolic responses dur...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biochim Biophys Acta
Prif Awduron: Matsiukevich, Dzmitry, Piraino, Giovanna, Lahni, Patrick, Hake, Paul W., Wolfe, Vivian, O’Connor, Michael, James, Jeanne, Zingarelli, Basilia
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653443/
https://ncbi.nlm.nih.gov/pubmed/28579457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2017.05.027
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