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Identification of hydrolyzable tannins (punicalagin, punicalin and geraniin) as novel inhibitors of hepatitis B virus covalently closed circular DNA

The development of new agents to target HBV cccDNA is urgently needed because of the limitations of current available drugs for treatment of hepatitis B. By using a cell-based assay in which the production of HBeAg is in a cccDNA-dependent manner, we screened a compound library derived from Chinese...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antiviral Res
Egile Nagusiak: Liu, Chunlan, Cai, Dawei, Zhang, Lin, Tang, Wei, Yan, Ran, Guo, Haitao, Chen, Xulin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5653380/
https://ncbi.nlm.nih.gov/pubmed/27591143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.08.026
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