Transcription of Hepatitis B Virus Covalently Closed Circular DNA Is Regulated by CpG Methylation during Chronic Infection

The persistence of hepatitis B virus (HBV) infection is maintained by the nuclear viral covalently closed circular DNA (cccDNA), which serves as transcription template for viral mRNAs. Previous studies suggested that cccDNA contains methylation-prone CpG islands, and that the minichromosome structur...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zhang, Yongmei, Mao, Richeng, Yan, Ran, Cai, Dawei, Zhang, Yijun, Zhu, Haoxiang, Kang, Yaoyue, Liu, Hongyan, Wang, Jinyu, Qin, Yanli, Huang, Yuxian, Guo, Haitao, Zhang, Jiming
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2014
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4206413/
https://ncbi.nlm.nih.gov/pubmed/25337821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0110442
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