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Aberrant rhythmic expression of cryptochrome2 regulates the radiosensitivity of rat gliomas

In this study, we investigated the role of the clock regulatory protein cryptochrome 2 (Cry2) in determining the radiosensitivity of C6 glioma cells in a rat model. We observed that Cry2 mRNA and protein levels showed aberrant rhythmic periodicity of 8 h in glioma tissues, compared to 24 h in normal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Fan, Wang, Caiyan, Li, Ling, Zhu, Jiayun, Zhao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652816/
https://ncbi.nlm.nih.gov/pubmed/29100427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20835
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