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Aberrant rhythmic expression of cryptochrome2 regulates the radiosensitivity of rat gliomas

In this study, we investigated the role of the clock regulatory protein cryptochrome 2 (Cry2) in determining the radiosensitivity of C6 glioma cells in a rat model. We observed that Cry2 mRNA and protein levels showed aberrant rhythmic periodicity of 8 h in glioma tissues, compared to 24 h in normal...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Fan, Wang, Caiyan, Li, Ling, Zhu, Jiayun, Zhao
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652816/
https://ncbi.nlm.nih.gov/pubmed/29100427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20835
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