Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

Mammalian metabolism is highly circadian and major hormonal circuits involving nuclear hormone receptors (NRs) display interlinked diurnal cycling(1,2). However, mechanisms that logically explain the coordination of NRs and the clock are poorly understood. Here we show that two circadian co-regulato...

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Main Authors: Lamia, Katja A., Papp, Stephanie J., Yu, Ruth T., Barish, Grant D., Uhlenhaut, N. Henriette, Jonker, Johan W., Downes, Michael, Evans, Ronald M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245818/
https://ncbi.nlm.nih.gov/pubmed/22170608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10700
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