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Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties

Ewing sarcoma (EWS) is a highly aggressive and metabolically active malignant tumor. Metabolic activity can broadly be characterized by features of glycolytic activity and oxidative phosphorylation. We have further characterized metabolic features of EWS cells to identify potential therapeutic targe...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Dasgupta, Atreyi, Trucco, Matteo, Rainusso, Nino, Bernardi, Ronald J., Shuck, Ryan, Kurenbekova, Lyazat, Loeb, David M., Yustein, Jason T.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652780/
https://ncbi.nlm.nih.gov/pubmed/29100387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20467
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