miR-130b directly targets Arhgap1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma

Ewing Sarcoma (ES) is a highly aggressive bone tumor with peak incidence in the adolescent population. It has a high propensity to metastasize, which is associated with dismal survival rates of approximately 25%. To further understand mechanisms of metastasis we investigated microRNA regulatory netw...

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Detalhes bibliográficos
Publicado no:Int J Cancer
Main Authors: Satterfield, Laura, Shuck, Ryan, Kurenbekova, Lyazat, Allen-Rhoades, Wendy, Edwards, Dean, Huang, Shixia, Rajapakshe, Kimal, Coarfa, Cristian, Donehower, Lawrence A., Yustein, Jason T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603410/
https://ncbi.nlm.nih.gov/pubmed/28748534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30909
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