Targeting the HGF/c-MET pathway: stromal remodelling in pancreatic cancer

Stromal-tumor interactions in pancreatic cancer (PC) impact on treatment outcomes. Pancreatic stellate cells (PSCs) produce the collagenous stroma of PC and interact with cancer cells to facilitate disease progression. A candidate growth factor pathway that may mediate this interaction is the hepato...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Pothula, Srinivasa P., Xu, Zhihong, Goldstein, David, Merrett, Neil, Pirola, Romano C., Wilson, Jeremy S., Apte, Minoti V.
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652738/
https://ncbi.nlm.nih.gov/pubmed/29100344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20822
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