Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model

Adult pleomorphic rhabdomyosarcoma (RMS) is a rare and recalcitrant, highly-malignant mesenchymal tumor in need of improved therapeutic strategies. Our laboratory pioneered the patient-derived orthotopic xenograft (PDOX) nude mouse model with the technique of surgical orthotopic implantation (SOI)....

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Udgivet i:Oncotarget
Main Authors: Igarashi, Kentaro, Kawaguchi, Kei, Kiyuna, Tasuku, Murakami, Takashi, Miwa, Shinji, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Singh, Arun S., Kimura, Hiroaki, Hayashi, Katsuhiro, Yamamoto, Norio, Tsuchiya, Hiroyuki, Eilber, Fritz C., Hoffman, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652670/
https://ncbi.nlm.nih.gov/pubmed/29100276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16548
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