Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model

Adult pleomorphic rhabdomyosarcoma (RMS) is a rare and malignant mesenchymal tumor. Recently, we developed a patient-derived orthotopic xenograft (PDOX) model of adult pleomorphic RMS. In the present study, we evaluated the efficacy of tumor-targeting Salmonella typhimurium (S. typhimurium) A1-R com...

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Publicado en:Transl Oncol
Main Authors: Igarashi, Kentaro, Kawaguchi, Kei, Zhao, Ming, Kiyuna, Tasuku, Miyake, Kentaro, Miyake, Masuyo, Nelson, Scott D., Dry, Sarah M., Li, Yunfeng, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Higuchi, Takashi, Singh, Shree Ram, Tsuchiya, Hiroyuki, Hoffman, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado: Neoplasia Press 2019
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Original article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6940643/
https://ncbi.nlm.nih.gov/pubmed/31896528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2019.10.005
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