Treatment of Patients With Metastatic Cancer Using a Major Histocompatibility Complex Class II–Restricted T-Cell Receptor Targeting the Cancer Germline Antigen MAGE-A3

PURPOSE: Adoptive transfer of genetically modified T cells is being explored as a treatment for patients with metastatic cancer. Most current strategies use genes that encode major histocompatibility complex (MHC) class I–restricted T-cell receptors (TCRs) or chimeric antigen receptors to geneticall...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Lu, Yong-Chen, Parker, Linda L., Lu, Tangying, Zheng, Zhili, Toomey, Mary Ann, White, Donald E., Yao, Xin, Li, Yong F., Robbins, Paul F., Feldman, Steven A., van der Bruggen, Pierre, Klebanoff, Christopher A., Goff, Stephanie L., Sherry, Richard M., Kammula, Udai S., Yang, James C., Rosenberg, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2017
Assuntos:
Original Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652397/
https://ncbi.nlm.nih.gov/pubmed/28809608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2017.74.5463
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