Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL

The current study investigated the effect of pyrrolidine dithiocarbamate (PDTC) on the proliferation, apoptosis, cell cycle and sensitivity to temozolomide (TMZ) of the U251 glioma cell line. Proliferation, apoptosis and cell cycle analysis of U251 cells following treatment with PDTC and TMZ was det...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncol Lett
Päätekijät: Tang, Jun-Hai, Huang, Guo-Hao, Mou, Ke-Jie, Zhang, Eric Erquan, Li, Ningning, Du, Lei, Zhu, Xiao-Peng, Chen, Ling, Yang, Hui, Zhang, Ke-Bin, Lv, Sheng-Qing
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: D.A. Spandidos 2017
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652242/
https://ncbi.nlm.nih.gov/pubmed/29098021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6849
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