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Pyrrolidine dithiocarbamate sensitizes U251 brain glioma cells to temozolomide via downregulation of MGMT and BCL-XL

The current study investigated the effect of pyrrolidine dithiocarbamate (PDTC) on the proliferation, apoptosis, cell cycle and sensitivity to temozolomide (TMZ) of the U251 glioma cell line. Proliferation, apoptosis and cell cycle analysis of U251 cells following treatment with PDTC and TMZ was det...

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Dades bibliogràfiques
Publicat a:Oncol Lett
Autors principals: Tang, Jun-Hai, Huang, Guo-Hao, Mou, Ke-Jie, Zhang, Eric Erquan, Li, Ningning, Du, Lei, Zhu, Xiao-Peng, Chen, Ling, Yang, Hui, Zhang, Ke-Bin, Lv, Sheng-Qing
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652242/
https://ncbi.nlm.nih.gov/pubmed/29098021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6849
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