Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

Cytoplasmic aggregation of fused in sarcoma (FUS) is detected in brain regions affected by amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which compose the disease spectrum, FUS proteinopathy. To understand the pathomechanism of ALS-FTD-associated FUS, we examined the behavio...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Shiihashi, Gen, Ito, Daisuke, Arai, Itaru, Kobayashi, Yuki, Hayashi, Kanehiro, Otsuka, Shintaro, Nakajima, Kazunori, Yuzaki, Michisuke, Itohara, Shigeyoshi, Suzuki, Norihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652009/
https://ncbi.nlm.nih.gov/pubmed/28928015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.09.005
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