Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma

Cytoplasmic aggregation of fused in sarcoma (FUS) is detected in brain regions affected by amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), which compose the disease spectrum, FUS proteinopathy. To understand the pathomechanism of ALS-FTD-associated FUS, we examined the behavio...

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Dades bibliogràfiques
Publicat a:EBioMedicine
Autors principals: Shiihashi, Gen, Ito, Daisuke, Arai, Itaru, Kobayashi, Yuki, Hayashi, Kanehiro, Otsuka, Shintaro, Nakajima, Kazunori, Yuzaki, Michisuke, Itohara, Shigeyoshi, Suzuki, Norihiro
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652009/
https://ncbi.nlm.nih.gov/pubmed/28928015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.09.005
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