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Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome

Worldwide medicinal use of cannabis is rapidly escalating, despite limited evidence of its efficacy from preclinical and clinical studies. Here we show that cannabidiol (CBD) effectively reduced seizures and autistic-like social deficits in a well-validated mouse genetic model of Dravet syndrome (DS...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Kaplan, Joshua S., Stella, Nephi, Catterall, William A., Westenbroek, Ruth E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651774/
https://ncbi.nlm.nih.gov/pubmed/28973916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711351114
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