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Cannabidiol attenuates seizures and social deficits in a mouse model of Dravet syndrome

Worldwide medicinal use of cannabis is rapidly escalating, despite limited evidence of its efficacy from preclinical and clinical studies. Here we show that cannabidiol (CBD) effectively reduced seizures and autistic-like social deficits in a well-validated mouse genetic model of Dravet syndrome (DS...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kaplan, Joshua S., Stella, Nephi, Catterall, William A., Westenbroek, Ruth E.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5651774/
https://ncbi.nlm.nih.gov/pubmed/28973916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1711351114
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